GRADE Method for Clinical Guidelines Development
Date: 28th - 29th February 2024
International Faculty
Bram Rochwerg
Gordon Guyatt
Laura Evans
National Coordinators
Gunjan Chanchalani
Mahesh Sinha
Local Coordinators
Jayanta Sharma
Rimita Dey
Course Description:
Learn from Prof. Gordon Guyatt himself, the Co-Chair of the GRADE Working Group, and other Experts.
The GRADE(Grading of Recommendations, Assessment, Development, and Evaluation) approach was developed by the GRADE Working Group, a collaboration of methodologists, guideline developers, clinicians, and other interested members, as a common, transparent, and sensible method of grading the quality of evidence and the strength of recommendations in guidelines. This approach is being used by many international organizations to produce rigorous and transparent clinical practice guidelines and other health care recommendations.
This workshop will help you become familiar with GRADE methodology and understand EBM concepts. It will facilitate the understanding of the basic principles of guideline methodology, including how to critically appraise the evidence, grade the quality of the evidence, and move from evidence to recommendations by using GRADE methods.
Day 1 - 28th February 2024 | |
Time | Topic |
09:00 - 09:15 | Introductions |
09:15 - 09:45 | GRADE Fundamentals including target of certainty rating |
09:45 - 10:30 | Systematic Review overview |
10:30 - 10:50 | Tea Break |
10:50 - 11:30 | Structured Clinical Question (PICO) Exercise (split into 2 groups) Diabetes example |
11:30 - 12:00 | 5 reasons to rate down (in two groups) |
12:00 - 13:00 | Lunch |
13:00 - 13:30 | Risk of bias |
1330 - 1420 | Rating Imprecision |
14:20 - 15:20 | Rating Inconsistency |
1520 - 1540 | Break |
15:40 - 16:05 | Rating Indirectness & Publication Bias |
1605 -1620 | Rating up Certainty |
16:20 - 16:30 | Overall Certainty of Evidence |
Day 2 - 29th February 2024 | |
Time | Topic |
09:00 - 10:00 | Subgroup Analysis |
10:00 - 11:00 | NMA including GRADE |
11:00 - 11:20 | Break |
11:20 - 12:00 | Guideline Development (panel composition, addressing COI, guideline presentation) |
12:00 - 13:00 | Lunch |
13:00 - 13:30 | Guideline Grab-bag: Absolute Effects, Plain Language Summary, EtD, Strength of Recommendation, Good Practice Statements |
13:30 - 13:45 | More on values and preferences |
13:45 - 14:00 | When low certainty evidence can permit strong recommendations |
14:00 - 15:00 | Developing recommendations for CAP exercise (split into 2 groups) |
15:00 - 15:20 | Break |
15:20 - 16:00 | Wrap Up and Takeaways |
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